SL Paper 3
In an experiment to determine the effect of diet on response to leptin, mice were fed a control diet or a high fructose diet for six months and then either injected with a saline (salt) solution or injected with leptin. The food intake of both groups was then monitored over a 24 hour period.
Leptin is a hormone. Hormones are chemicals produced in one part of the body that have an effect in another part of the body.
Distinguish between the effect of leptin injection on 24 hour food intake in the mice fed the control diet and in the mice fed the high fructose diet.
Discuss the implications of these results for recommending leptin injections as an appetite suppressant for humans.
State the tissue that produces leptin in humans.
State the target that leptin normally acts on.